CancerHSP
Molecule Information
Molecule IDMol3313
Molecule namegenkwadaphnin
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Pharmacological and molecular properties
InChIKeyQKMXESBAFIKRAD-CZAUBJEPSA-N
FormularC34H34O10
ActivityLewis lung carcinoma (LLC)-inoculated mice, reduction of tumor volume is 47.9%(0.1 mg/kg) and 63.1%(0.5 mg/kg); HL-60, IC50=11.8±0.89μM(48h); SNU-1, IC50=26.7±1.45μM(48h);
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Reference[1] Park B Y, Min B S, Ahn K S, et al. Daphnane diterpene esters isolated from flower buds of Daphne genkwa induce apoptosis in human myelocytic HL-60 cells and suppress tumor growth in Lewis lung carcinoma (LLC)-inoculated mouse model[J]. Journal of Ethnopharmacology, 2007, 111(3): 496-503.
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