| Molecule ID | Mol2153 |
|---|---|
| Molecule name | (+)-6,6'-Methoxygossypol |
| Download structure (click to download) |  |
| Pharmacological and molecular properties | |
| InChIKey | OUHOXIPLBJIWEG-UHFFFAOYSA-N |
| Formular | C32H34O8 |
| Activity | MCF-7, IC50=4.00μg/ml; HeLa, IC50>5μg/ml; HT29, IC50=3.00μg/ml; KB, IC50>5μg/ml; human breast MCF-7; human colon Caco-2; and cervical SiHa; 16.8ppm gossypol scavenge 50% of the free radicals; T. brucei cell, IC50=3.21ppm |
| CAS | ♦ |
| Molecule synonyms | |
| Related targets | |
| Related Herbs | |
| Reference | [1] Boonsri S, Karalai C, Ponglimanont C, et al. Cytotoxic and antibacterial sesquiterpenes from Thespesia populnea[J]. Journal of natural products, 2008, 71(7): 1173-1177. [2] Wang X, Beckham T H, Morris J C, et al. Bioactivities of gossypol, 6-methoxygossypol, and 6, 6′-dimethoxygossypol[J]. Journal of agricultural and food chemistry, 2008, 56(12): 4393-4398. |