CancerHSP
Molecule Information
Molecule IDMol1151
Molecule name5,6,4'-Trihydroxy-7,3'-dimethoxyflavone
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Pharmacological and molecular properties
InChIKeyLRUIASUJJNMESX-UHFFFAOYSA-N
FormularC17H14O7
ActivitySW620, GI50=5.0±0.4μM (control: Doxorubicin, GI50=0.34μM); A549, GI50=11±3μM (control: Doxorubicin, GI50=0.21μM); PC3, GI50=3.4±0.3μM (control: Doxorubicin, GI50=0.0.39μM); LOX-IMVI, GI50=2.6±0.3μM (control: Doxorubicin, GI50=0.12μM); HCT15, GI50=4.1±0.3μM (control: Doxorubicin, GI50=0.84μM); SW620 cells, 0.5% tween 80, ip60mg/ (kg.d)22d tumor volum reduce 14.6%
CAS♦ 25782-25-6
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Reference[1] Zhou, J., Xie, G. and Xinjian, Y. (2012) Anticancer active components in TCM. TCM series of active components. Science Press, Bei Jing.
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