CancerHSP
Molecule Information
Molecule IDMol2157
Molecule name(+)-Isotrilobine
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Pharmacological and molecular properties
InChIKeySVMNNRZZJAFEJM-IZLXSDGUSA-N
FormularC36H36N2O5
ActivityHepG2, IC50=0.6μg/mL(?h); Hep3B, IC50=0.75μg/mL(?h); MCF-7, IC50=3.9μg/mL(?h); MDA-MB-231, IC50=1.6μg/mL(?h); (Control: taxol, HepG2, IC50=0.18μg/mL(?h); Hep3B, IC50=0.08μg/mL(?h); MCF-7, IC50=0.14μg/mL(?h); MDA-MB-231, IC50=0.12μg/mL(?h);)
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Related Herbs
Reference[1] Chang F R, Wu Y C. New bisbenzylisoquinolines, fatty acid amidic aporphines, and a protoberberine from Formosan Cocculus orbiculatus[J]. Journal of natural products, 2005, 68(7): 1056-1060.
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