TCMSP is a unique systems pharmacology platform of Chinese herbal medicines that captures the relationships between drugs, targets and diseases.
The database includes chemicals, targets and drug-target networks, and associated drug-target-disease networks, as well as pharmacokinetic properties for natural compounds involving oral bioavailability, drug-likeness,intestinal epithelial permeability, blood-brain-barrier, aqueous solubility and etc.
This breakthrough has sparked a new interest in the search of candidate drugs in various types of traditional Chinese herbs.
(1) Herbal information.
(2) ADME data for each compound.
(3) Targets information.
(4) Diseases information.
(5) Pathway information.
The searching results include: all compounds with 3D structures, ADME data, drug-target networks, target-disease networks. Moreover, this platform also provides a chemical screening process based on ADME features.